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Re: [IPk] Lyumjev insulin



thatbs really interesting - whatbs the scientific explanation for the pain?
Di

 > On 18 Nov 2020, at 15:51, Tim Street
<email @ redacted> wrote:
> 
> I've used it and so have many others across Europe. What I've found is
> detailed at https://www.diabettech.com/Lyumjev
> 
> If that's tldr, then I'd sum it up as the first week was awful and it
> didn't work at all well and hurt like hell, with me waking up when I rolled
> on to the infusion site in the night due to the pain.  I switched to mixing
> it 50:50 with Fiasp, which worked well and removed pain while retaining
> relatively fast speed.
> 
> Others have seen a range of issues from nothing to similar pain. A number
> have stopped because of the pain.
> 
> Move forward 2.5 months and I was able to switch back and now I'm on 100%
> Lyumjev with no pain.  It works really quickly and I've had great TIR of
> 90% for the last month (bear in mind I'm using an open source closed loop).
> 
> The key additive that makes it faster is Treprostinil and it's normally
> used subcutaneously for Pulmonary Hypertension. The papers I've found on
> that say that it usually causes site pain for a couple of months when used
> in that fashion which eventually subsides, so its no surprise that a lot of
> people have reported site pain.
> 
> Tim Street
> 
> +44 (0) 7740 051460
> 
> On Wed, 18 Nov 2020, 12:57 Ken Tieszen, <
> email @ redacted> wrote:
> 
>> I have decided to change from humalog to lyumjev insulin, and wonder if
>> anyone
>> else has tried or is using this insulin. Lyumjev is the new type of lispro
>> that
>> contains citrate which helps to speed absorption. NICE reports that it is
>> 11 min
>> quicker than humalog (lispro) and duration is about 40 min shorter. I am
>> hoping
>> that it will help me better control post-prandial glucose levels.Ken
>> .
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