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RE: [IPk] Re: glucowatch

John asked:

Pigs' beta-cells anyone?

I've read about possibly transplanting pigs' beta cells, but one of the 
myriad concerns would be transgenic diseases.

Can diseases be transmitted using animal insulin?  If the answer is yes, and 
presuming transplanting pigs' cells (or any other animals') works, is there 
any real difference?



>From: John Neale <email @ redacted>
>Reply-To: email @ redacted
>To: email @ redacted
>Subject: RE: [IPk] Re: glucowatch
>Date: Tue, 3 Jul 2001 11:31:29 +0200
> >Why does it all take so long?
>How many billion do you have? MiniMed was established by Alfred Mann 20
>years ago specifically to develop the artificial pancreas. It's become a
>successful profitable company, and has been taken over by an even more
>successful profitable company. Enormous progress has been made. But nobody
>has been able to bring anything reliable to the market place. Disetronic
>are trying. But their DiaPort (which delivers insulin direct to the portal
>vein where it should go) has not yet won widespread use. Animas are trying.
>They have an implanted sensor, so it doesn't matter what your skin is
>doing. But no product has reached market. Others are trying. They are
>spending millions between them. But as we are seeing with GlucoWatch, when
>you bring the product to the market place, it does not perform as required.
>The GlucoWatch will not give you your bg at the awkward times when you most
>need it: when you are exercising, when you are having a bath, when you have
>run for a bus and got all sweaty, or even - heavens above - when you have
>got all sweaty because you are having a hypo!
>I was very excited when NASA decided they also needed constant bg
>monitoring for their handful of astronauts, and NASA=$$$, but still nothing
>successful has appeared.
>There's always that elusive thing: regulatory approval. The assurance that
>under some obscure conditions the product will not fail and kill you. How
>does the pump decide that the unusual readings it's getting from the
>GlucoWatch should be responded to (you've drunk a bottle of Lucozade...) or
>should be ignored (you spilt the Lucozade on the watch...)? These are very
>real situations that even Anthony's finest algorithms may be powerless to
>distinguish between, short of sounding an alarm 10 times a day when
>anything interesting happens.
>I don't mean to be pessimistic, and I have great hope for the near future,
>but there is golden rule in medicine that new exciting projects generally
>deliver about 10% of what was hoped for.
>Pigs' beta-cells anyone?
>mailto:email @ redacted
>for HELP or to subscribe/unsubscribe, contact: HELP@insulin-pumpers.org
>help SUPPORT Insulin Pumpers http://www.insulin-pumpers.org/donate.shtml

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