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Re: [IPk] Re: insulin sensitivity : pulses or continuous del

> >Time intervals between pulses was 30 , 60 and 120 minutes .
> >The results showed that the plasma glucose levels were the same whether
> >the insulin was given continuously or intermittently and in both cases
> >they remained stable .
> >Free insulin levels were the same with continuous and pulsed insulin .
> >
> >The study conclusion was that the similarity in metabolic control between
> >the 2 groups demonstrates the wide physiological limits for sc basal
> >insulin replacement .Both pulses and continual trickles of insulin
> >provided the same results in terms of control and free insulin levels .
> I've not read the paper, Morag. But what insulin were they testing?
> A lot of us here use Humalog, and I would be very surprised if a
> small injection of Humalog every 2 hours delivered a stable basal
> rate.

A little math and the insulin availability curves from the package 
insert should convince you with no difficulty. It produces a pretty 
smooth curve.
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