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Re: [IPk] Insensitivity



Hi Paul ,
How many units of insulin are you using per day ?
It is only young children who dilute to U40 . We have many pump users with high insulin sensitivity and they achieve very good contril with the Minimed pump . Infact those requiring small insulin doses are a good selection criteria for pump therapy .

A normal pancreas delivers a small pulse of insulin approx. every 6 - 7 minutes and so the Minimed pulses of .1 units approx. every 6 minutes  with a basal rate of 1u/hr [ which is the average ] provides extremely physiological delivery .

Paul , you may benefit from wearing a glucose sensor [ cgms from Minimed ] as this will help you to identify the periods of the day and night when you need varying doses of insulin . The cgms can help you to fine tune your requirements for both basal and bolus delivery .

Feel free to send me your details , privately and we can try to help you improve your control ,

Best wishes
Morag
----- Original Message ----- 
From: paulleonard <email @ redacted>
To: <email @ redacted>
Sent: 27 August 2001 19:12
Subject: [IPk] Insensitivity


> Hi all!
> 
> John wrote "...with that degree of sensitivity I'm guessing that U100 Humalog
> might be inappropriate, since at U100, the Minimed pump delivers it in 0.1
> unit bursts.  On a very low basal rate, you could effectively run out of
> insulin between these bursts.  I hear that in the US some people dilute their
> Humalog down to U40 using a special Lilly solution."
> 
> Your assumption was correct, John, I do use U100 Humalog, and as well as the
> issue with the remote I often find that only having a few (as low as two on my
> smallest basal rate) basal boluses per hour means I can't fine-tune control.
> I only realised that Disetronic pumps can deliver much smaller aliquots more
> frequently a couple of months ago, and I'd bought my own MiniMed by then, a
> lesson there (perhaps those who advise would-be pumpers on the pros and cons
> of the different pumps could bear this in mind too!). The dilution idea sounds
> very sensible, I would have to change the pump syringe more frequently but
> that would be a small price to pay for better control.  I will investigate!
> 
> Sorry to hear about your modem, Elizabeth, hope it recovers soon, and look
> forward to the rescheduled Chat.
> 
> Mary
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