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Re: [IPk] Glucophage



Hi John, I didn't realise you were in Belgium. I've just come back from
Brussels, is that where you're based? If so, maybe we can meet up next time.

Glucophage is one of the more common drugs used in type 2 diabetes. It does
several things, like increase the use of glucose in the liver certainly, but
its main action seems to be to squeeze more insulin from the islet cells. It
wouldn't make a lot of sense to use it in well-developed type 1, because the
islet cells don't have any glucose left no matter how much you squeeze them!
There might be a case in the early 'honeymoon' days of type 1, when some
production still exists, but to be honest I've never heard of that.

On the other hand, many Euro countries start insulin early in type 2, and
that is probably what is hapenning here. There goes your colleague's street
credibility!!

Regards,

Tony O'Sullivan
----- Original Message -----
From: "John Neale" <email @ redacted>
To: <email @ redacted>
Sent: Saturday, April 20, 2002 10:36 AM
Subject: [IPk] Glucophage


> Does anyone know much about glucophage?
>
> I've met a guy (he's actually a work colleague) who, like me, is British
> but is working in Belgium. He was diagnosed with Type 1 diabetes here in
> Belgium 6 years ago, at the tender age of 39. He was put on a regime of 3x
> Actrapid and 1x Insulatard (pre-bed) and 2x glucophage. If I remember
> rightly, glucophage stops the liver dumping glucose into the blood. Is
that
> right? Seems that different countries have different attitudes towards its
> use.
>
> The guy, who appears in general good health, also claims to have not
tested
> his blood glucose for "several months". There we are.
>
> John
>
> --
> mailto:email @ redacted
> http://www.webshowcase.net/johnneale
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