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[IPp] bubbles in the line

We have a minimed 508 and with both quickset and silhouette, we find that 
when we prime both manually and with the pump that we cannot get rid of large 
bubbles, no matter how much insulin we push out of the reservoir.  We have 
been told there is backflow problems with the 508.   
Does anyone have any experience out there?
Miriam, mom of Sarah
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