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RE: [IPm] CASE



That is a good point about the intraperitoneal insulin.  It has the
advantage of being able to use large amounts of insulin.  I was involved
in the implanted insulin pump (MiniMed) with type 1s and the UCSF
with type 2.

We brought up the use of a simple catheter and the usual external pump
but MiniMed never commented on that.  You could at least see if there
was any advantage to such a system very quickly.  They were using
U 500 insulin.

Dr. Joe

-----Original Message-----
From: email @ redacted
[mailto:email @ redacted]On Behalf Of Van Antwerp, Bill
Sent: Friday, September 17, 2004 11:06 AM
To: email @ redacted
Subject: RE: [IPm] CASE


 Michael: Why not an implantable pump, that would appear to be the most
efficacious use of resources and we know that IP delivery has a lot of
benefits.

BVA

-----Original Message-----
From: email @ redacted
[mailto:email @ redacted]On Behalf Of Michael
Sent: Friday, September 17, 2004 9:20 AM
To: email @ redacted; email @ redacted
Subject: [IPm] CASE


I received this from a colleague. Your comments would be appreciated
email @ redacted

------- Forwarded message follows -------
Subject:        	Date sent:      	Thu, 16 Sep 2004 21:09:58 -0500
From:           	"Dimeglio, Linda A" <email @ redacted>
To:             	<email @ redacted>


Michael -
I have a 12 year old kid with Rabson-Mendenhall (profound insulin
resistance due to insulin receptor mutations) that I want to start on a
pump with U500 insulin - I've gotten approval to put him on a Cozmo -
but wanted to see if there was anyone "out there" that had experience
with high volumes of insulin in pumps or U500 in pumps - He's currently
getting about 250 units/day of U500 (or 1250 units/day of U100
equivalent) - and his A1C's are still in the 13's.

Thanks!

Linda

Linda A. DiMeglio, MD
Assistant Professor
Pediatric Endocrinology/Diabetology
Indiana University
email @ redacted
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