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[IPm] Pruritis with Humalog and Novolog

Any suggestions:

40 y.o. Male, type I DM X 10 years.  Humalog pump x 2 years with no
problems.  Developed severe pruritis, no rash, no site problems.  Resolved
at once on Humilin-L injections.  Converted to Novolog pump therapy for 6
months with no problems, then intense pruritis.  Again, no urticaria or site
problems. Resolved with Humilin-L injections and discontinuation of pump.

Is this an allergy to insulin analogs, or to m-cresol preservative ?  How
does one test for this?  Can this be a true allergic response in the absence
of urticaria ?


Tip McKnight
Insulin-Pumpers website http://www.insulin-pumpers.org/
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