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RE: [IP] RE: aspirin / High aspirin dosage may curb heart attack risk in diabetes

Ricardo, Thank You for the information. The problem today is we are
inundated with Information, GOOD and BAD.
Most of the studies are funded by Pharmaceuticals, and orientated to make
them money. Most medical news is presented to make money for somebody. Even
University research programs are funded by Big Pharma. It is hard for me ,
No PHD in medicine, to make decisions on what to do or not. I rely on my
Primary and Endo for most of the information. But I am like everyone else.
We are looking for the magic pill or shot or diet or exercise program that
will eliminate our problems.
This is what Big Pharma and Businesses relies on. If we buy just I bottle of
DIABETES CURE, that is a possibility of 30 million people. Somebody will
make lots of money. 

John S Wilkinson, Rome, NY
"A  veteran  is someone who, at one point in his or her life, wrote a blank
check made payable to The 'United States of America', for an amount of up to
and including their life." (Author unknown)
Be very, very careful what you put into that head, because you will never,
ever get it out. Thomas Cardinal Wolsey (1471-1530)

-----Original Message-----
From: email @ redacted
[mailto:email @ redacted] On Behalf Of Ricardo
Sent: Friday, July 08, 2011 11:37 AM
To: email @ redacted
Subject: [IP] RE: aspirin / High aspirin dosage may curb heart attack risk
in diabetes

John Wrote:
 High aspirin dosage may curb heart attack risk in diabetes Increasing
dosage may help curb heart attack risk in patients with diabetes, according
researchers at the University of Alberta in Canada. A researcher said those
had daily doses of up to 325 milligrams of aspirin had 23% reductions in
cardiovascular-related mortality.

What do we do?

Ricardo Responds:
Hi John,

 Not to discredit the results, but I would use some caution in interpreting
results of this study.

 This study did not actually run a controlled study that compared high dose
aspirin vs. low dose vs. no aspirin subjects. The study is a meta-analysis
studies done over the last 30 or so years and so it is simply a statistical
analysis of data.

 A criticism of meta analysis is the lack of control for bias and
Were the high dose aspirin users more health conscious and therefore less
susceptible to CHD? Did they smoke less than the control group? How did
body weight compare to a control group? What other medications did the high
subjects take? In addition, the conclusion seems to violate the basic
principle that "correlation does not necessarily imply causation". Saying
those who took high dose aspirin had less CHD mortality, therefore high dose
aspirin decreases CHD mortality is no more proof of theory than saying that
roosters crow before the sun rises, therefore roosters cause the sun to

 It is also well known that CHD mortality has in general decreased over the
year time span of this study, yet CHD morbidity has increased. This study
addresses a decrease in mortality, with no mention of morbidity. So the
agrees with a general trend that was already in place, so the best we may be
able to say is that high dose aspirin is a contributing factor to decreasing
risk of dying from CHD, but not preventing CHD, which I am assuming is the
ultimate goal for most diabetics.

 The anti-inflammatory, blood thinning effects of aspirin are well known,
long term high dose usage can have side effects in some people. Google can
you to some more natural alternatives.

More on the study can be seen here:

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