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[IP] Type 1 and Type 2 in the same person

We have periodically discussed this phenomenon, and now there is some
research evidence:
>From "Diabetes In Control" newsletter:

Coexistence of Type 1 and Type 2 diabetes?
During the same session the fascinating concept of the coexistence of Type
1 and Type 2 diabetes was discussed by Dr Damci, presenting research
comparing insulin sensitivity, blood pressure, waist circumference and
lipid profiles of Type 1 diabetic patients with and without first-degree
relatives with Type 2 diabetes.
Type 1 diabetic patients who have first-degree relatives with Type 2
diabetes tend to be more insulin-resistant, have higher systolic and
diastolic blood pressures, larger waist circumferences and more
dyslipidaemia, all features resembling the metabolic syndrome. It may
therefore be possible that in some patients with Type 1 diabetes, Type 2
diabetes coexists.

Why would patients with Type 1 diabetes be spared from the metabolic
syndrome? Certainly, -cell dysfunction will not play a role in these
patients, but insulin resistance and other features of the metabolic
syndrome will. This could account for the beneficial effects of metformin
in some Type 1 diabetic patients.

It seems advisable to be alert for features of the metabolic syndrome in
Type 1 diabetic patients, to treat them aggressively, and also to consider
treatment with insulin-sensitizing drugs.

Barbara A. Bradley, MS, RN, CDE

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