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Re:[IP] slow onset and Type 1

The ADA book on the Clinical Management of Type 1 Diabetes has a schematic
chart illustrating the time line from the onset of islet cell destruction to
the diagnosis of Type 1. Interestingly, the time frame includes an "unknown"
frame that is not predictable. As the funtioning islet cells decrease, there
is a point in time where the available insulin no longer controls the BG and
the "starvation" process occurs leading to the typical symptoms and DKA. The
process is thought to be accelerated during growth spurts and puberty.

I am sure the same schematic is also printed in the Diabetes Care, 2000
Supplement, Clinical Practice Recommendations, which can be accessed at the
ADA site: diabetes.org.

Barbara A. Bradley, MS, RN, CDE

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