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Re: [IP] Glucometer

As an insulin injector of more than 40 years i have difficulty in the idea
that Humalog takes 1 to 2 hours to be effective. My understanding is that
its peak activity is within a maximum of 30 mins and that when checking or
setting up afternoon basal levels 'Changing To Humalog?'
<http://www.diabetesnet.com/hmlgpmp.html> '...simply skip lunch and skip the
bolus of Humalog ordinarily taken to cover it. I find with Humalog
injections that there is basically no real residual action after two hours.
Am I missing the point?
Alan Reed <email @ redacted>
-----Original Message-----
From: Michael <email @ redacted>
To: email @ redacted <email @ redacted>
Date: 30 September 1998 02:21
Subject: Re: [IP] Glucometer

>> Michael:
>> MY nonengineer thought.  The pump could be made to respond to time
>> interval readings with an over-ride done by the wearer/user of the
>> pump.  Would this be to simple? Yale
>The problem lies in the design of the servo system. The feedback loop
>is so long, that by the time the insulin starts to be really
>effective ( 1 to 2 hours even for Humalog ) a low or a high would
>already be dramatically impacting the user of the equipment. I don't
>know about you, but my daughter can go from 100 to 40 or 200 in 30
>minutes if she has done something wrong with her planning or is
>simply exercising very heavily. This is much faster than the servo
>loop could respond given the action time of the insulin. That said,
>the action time for both lispro and regular are about the same if
>given intravenously (according to literature I've read). Things
>apparently start happening quickly ~15 minutes as opposed to an hour
>with lispro. This could be quick enough to design a reasonable
>control loop that should work OK although I'm not sure I would want
>to be the test subject when the machine thinks I'm high and I really
>on the way down.
>email @ redacted
>Insulin-Pumpers website http://www.bizsystems.com/Diabetes/

Insulin-Pumpers website http://www.bizsystems.com/Diabetes/