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[IP] Coffee and type 2 diabetes
Medscape Medical News 2002. ) 2002 Medscape
Nov. 8, 2002 Drinking more than seven cups of coffee
per day may reduce the risk of type 2 diabetes,
according to the results of a prospective population
study reported in the Nov. 9 issue of The Lancet.
"Coffee is a major source of caffeine, which has been
shown to acutely reduce sensitivity to insulin, but
also has potentially beneficial effects," write Rob M.
van Dam and Edith J.M. Feskens from the Dutch National
Institute for Public Health and the Environment in
Bilthoven, the Netherlands. They suggest that
magnesium in coffee could improve insulin sensitivity
and excretion, and that other components of coffee
such as chlorogenic acid could also lower risk of
In a population-based cohort of 17,111 Dutch adults
aged 30 to 60 years, there were 306 new cases of type
2 diabetes during 125,774 person-years of follow-up.
Individuals who drank seven or more cups of coffee
daily were 50% less likely to develop type 2 diabetes
compared with drinkers of two cups daily, even after
adjustment for confounding factors including smoking,
alcohol consumption, and body mass. Relative risk for
high coffee consumption was 0.50 (95% confidence
interval, 0.35-0.72, P=.0002).
"In view of the widespread use of coffee and the large
health burden of type 2 diabetes, our finding of an
inverse association between coffee consumption and
risk of type 2 diabetes could have important public
health implications," the authors write. "However, our
findings need to be replicated and possible adverse
effects on other health aspects should be considered
in the choice to consume coffee."
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