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Re: [IP] iv correction bolus

Hi John, seems this is a followup on a thread we had a year or more ago.
Yes, IV insulin will work exactly like it does in normal people, where it
is also injected by the beta cells directly into the blood.   In large
boluses it might linger a bit more than 10 min, but the initial effect will
be quite rapid.   There's no real danger with the IV injection (unless you
can't find the vein).  The skin normally is never sterilized even when you
get blood drawn in a clinic, and addicts don't even use sterile needles.
Of course one obviously shouldn't share your syringe with an addict or even
another diabetic :-)    The dose will be close but a little less than what
you would shoot subcutaneously.  I've never done it either, and likewise
would have trouble sticking one of my bulging veins.  I'm not sure I'd
bother to use it if my BG was only 300.  HOwever if BG got really high like
in the 500 range, then it might be a good thing to want to pull it down
quickly.  But I think having someone else around the first time would be
prudent.  Also getting an OK from some medical personell other than me :-)
would be even more prudent.   Let us know if you give it a try.  Me, i'm in
such good control that I would never need it.  Right :-), and I also have a
bridge in Brooklyn that I'd like to sell you too.
- -wayne

I recently met a German friend, who uses a pump, and she told me that a few
diabetes specialists in Germany now train some patients to take a
correction bolus intravenously - that is, you stick a needle in the large
vein in your arm, and inject a few units directly into the blood.

The beauty of this is that once it's in the blood, insulin is does its work
and is finished within about 10 minutes. If I were about to eat, and found
my bg was 300, I could lower it to my target of 120 within 10 minutes by
taking 3.6 units ( =(300-120)/50 ) intravenously. And I would know it
wasn't going to carry on falling any further.

Does anyone else do this? Or know anyone who does it? I've never done it
myself, and I'm rather squeemish about sticking needles into veins.

Obviously, you should *never* take a complete meal bolus intravenously,
since you would have a massive hypo after 10 minutes - long before the food
you were eating got digested. And you should *never* take long-acting
insulin intravenously, as the crystals would clog up your tiny blood
vessels. But a carefully measured couple of units sounds like an
interesting way of making fast controlled adjustments to your bg.


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