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[IP] Our children are fragile

Diabetes Care 1999 Mar;22 Suppl 2:B40-2 

Dead-in-bed syndrome in young diabetic patients.

Sovik O, Thordarson H

Department of Pediatrics, University Hospital, Bergen, Norway. 
email @ redacted 

The so-called dead-in-bed syndrome refers to sudden death in young 
diabetic patients without any history of long-term complications. 
Autopsy is typically negative. The present report summarizes frequency 
data on this condition from studies in the U.K. and the Scandinavian 
countries. It appears that such deaths occur in 6% of all deaths in 
diabetic patients below age 40 years. The frequency may also be 
expressed as 2-6 events per 100,000 patient-years. The causes are by 
definition unknown, but a plausible theory is a death in hypoglycemia, 
since a history of nocturnal hypoglycemia is noted in most cases. While 
waiting for the clarification of the underlying pathophysiology, one 
should attempt to identify patients who are at particular risk of 
hypoglycemia and advocate caution in efforts to normalize blood glucose 
and HbAlc in these cases. 

PMID: 10097898, UI: 99197971 
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