[Previous Months][Date Index][Thread Index][Join - Register][Login]
[Message Prev][Message Next][Thread Prev][Thread Next]

Re: [IP] Novolog vs. Humalog

> Hi Group!
> I'm looking for any websites with facts comparing the two insulins.
> Thank you very much,


Humalog and Novolog aka NovoRapid in the EU, are insulin analogs 
(lantus is also an insulin analog). This means that they are not 
really insulin at all. Their molecular structure has been altered 
somewhat to facilitate rapid absorption.

All modern insulins and insulin analogs are what is called "human"
insulin. That means that they are replications of human insulin
reproduced by recombinant DNA technology. In plain english, the
insulin is reproduced by bacteria in a vat.  Insulin and insulin
analogs are comprised of very long chains of molecules. The insulin
analogs are essentially identical to "real" insulin except that one
(Novlog) or two (Humalog) of the molecules have been moved or

In Humalog the amino acids at positions 28(lys) and 29(pro) on the
insulin B chain are reversed. In Novolog/NovoRapid, the amino acid
proline in position 28 of the insulin B chain is replace with a
molecule of aspartic.

Hope that helps.

email @ redacted
email @ redacted
for HELP or to subscribe/unsubscribe, contact: HELP@insulin-pumpers.org
send a DONATION http://www.Insulin-Pumpers.org/donate.shtml