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[IP] pump therapy at night only (anyone want to write a letter?)



Well, I know I have some words to share with this researcher.  Anyone else 
care to write to her?  Here's the abstract with her email addy.  (I posted 
the full article at
 <A HREF="http://www.islet.org/forum/messages/14734.htm">Pump at Night  in 
Children 7-10 with type 1</A> )

: Diabetes Care 2000 May;23(5):579-82Books 
Use of insulin pump therapy at nighttime only for children 7-10 years of 
age with type 1 diabetes. 
Kaufman FR, Halvorson M, Kim C, Pitukcheewanont P 
Department of Pediatrics, University of Southern California School of 
Medicine, USA. email @ redacted
[Medline record in process]
OBJECTIVE: Because of age-related developmental and cognitive issues, 
children <10 years of age may not be able to wear an insulin pump safely 
when they are not under direct parental supervision. The purpose of this 
study was to determine if insulin pump therapy at nighttime only, when 
children are at home, could improve fasting and nighttime blood glucose 
levels without adverse effects. RESEARCH DESIGN AND METHODS: The study 
cohort consisted of 10 children aged 7-10 years. A randomized crossover 
design was used to compare nighttime-only pump usage from dinner and 
throughout the night, combined with a prebreakfast injection of 
intermediate-acting NPH and rapid-acting lispro insulin, with 3 insulin 
injections per day. Comparisons were made among mean blood glucose 
values and percentage of blood glucose levels within the target range 
(70-150 mg/dl) before meals, at bedtime, and at 3:00 A.M.; serum 
fructosamine levels; and scores on measures of adherence and fear of 
hypoglycemia. RESULTS: Compared with baseline levels, the use of the 
pump resulted in a significant decrease in the mean average (P < 0.001), 
breakfast (P < 0.0001), and 3:00 A.M. (P < 0.003) blood glucose levels. 
There was a decrease in the percentage of blood glucose values less than 
the target range (P < 0.01) and in fructosamine (P < 0.01) values and an 
increase in the percentage of blood glucose levels within the target 
range (P < 0.03). CONCLUSIONS: Nighttime-only insulin pump therapy may 
be a viable alternative that young children can use to improve glycemia 
when they are not capable of independently managing an insulin pump.
PMID: 10834412, UI: 20292246  <A 
HREF="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&lis
t_uids=10834412&dopt=Abstract">Entrez-PubMed </A>  <A 
HREF="http://www.islet.org/forum/messages/14734.htm">Pump at Night  in 
Children 7-10 with type 1</A> 
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