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Re: [IP] Transplant organs without rejection

>     Transplant organs without rejection
>     Human trials expected in months
>     By Robert Bazell
>     NEW YORK, June 1 - There's been a breakthrough in organ
>     transplantation that could have astounding implications for all sorts
>     of diseases - even a potential cure for diabetes. "This type of
>     approach," said Dr. Allan Kirk of the Naval Medical Research Center in
>     Bethesda, Md., "could revolutionize transplant medicine."
>             SO FAR, the research has been done in monkeys only - but it
>     has been so successful that human trials will start within months.
>            Until now the problem with transplantation has been that the
>     body's immune system tries to reject transplanted tissue so vigorously
>     that some transplants are not possible - and others require a lifetime
>     of harsh anti-rejection drugs
>            In the new research, scientists were able to use a genetically
>     engineered drug to retrain the immune system, altering white blood
>     cells so that the body accepts the transplanted tissue without
>     anti-rejection drugs.
>            At the University of Miami, Dr. Norma Kenyon and Dr. Camillio
>     Ricordi, for the first time, successfully transplanted cells called
>     islets that manufacture insulin. Monkeys with a condition like
>     diabetes now can survive and stay healthy without insulin shots.
>      Dr. Norma Kenyon
>               "This appears to be a significant advance," said Kenyon,
>     "one step closer to what may eventually lead to a cure for type-1
>     diabetes."
>            That's amazing news for the almost one million Americans like
>     Jane Adams, of Washington, DC, who suffer form the most serious form
>     of diabetes, type-1. To keep their blood sugar at normal levels most
>     diabetics must constantly monitor their blood and inject insulin
>     several times a day. But even with insulin, diabetes can get out of
>     control bringing loss of eyesight and limbs, heart attacks and death.
>            "Theres an everyday burden of dealing with your diabetes," said
>     Adams. "But there's also an emotional and kind of frightening burden
>     about what lies ahead in the future."
>            Using the new transplantation technology, other scientists have
>     transplanted kidneys in monkeys - without using anti-rejection drugs.
>     If it works in humans, transplants will become much simpler.
>            "People could have their organ failure cured," said Kirk, "and
>     go about their normal daily life without being tethered by the side
>     effects of immunosuppressive medication."
>            That dream could become a reality as early as this summer, when
>     human trials begin of the new kidney transplant technique and the new
>     attempt at curing diabetes.
>            Robert Bazell is a science correspondent for NBC News.
>Insulin Pumpers website http://www.insulin-pumpers.org/
>for mail subscription assistance, contact: HELP@insulin-pumpers.org

Insulin Pumpers website http://www.insulin-pumpers.org/
for mail subscription assistance, contact: HELP@insulin-pumpers.org