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RE: [IP] Re: Use of oral agents in teenagers



Whatever you care to believe Cindy.

Margo



Margo,

The article substantiates what I said.  Type 1's can develop insulin
resistance due to acquiring extra weight, family history of Type 2,
etc. in which case they have both Type 1 and Type 2.  But Type 1, in
and by itself, does not include insulin resistance.

Copied and pasted from the URL you posted:

The IRS score is based on clinical risk factors in adults with type 1
diabetes, including hypertension, high waist-to-hip ratio, family
history of type 2 diabetes and glycemic control. By applying a
personalized rating of 1 (lowest) to 3 (highest) for each risk
factor, then dividing by the total
number of risk factors for which data are available, a physician can
calculate an IRS score for the patient.
The study included eight type 1 diabetic patients from each of three IRS
risk categories-low, moderate and high. The subjects received a clamp
study to measure GDR and thus verify their IRS scores.

"Previous research has identified a family history of type 2 diabetes as a
risk factor for insulin resistance in the general population, but this is
among the first to identify it as a risk factor in type 1 diabetics," said
Dr.
  Orchard. Research also has found that a family history of type 2
diabetes increases the risk of cardiovascular complications.
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