[IP] Re: Paradigm "upgradable"
I think you're missing something. The idea is that in order for the
pump to support giving 1 unit of U-200 insulin, it would ACTUALLY have
to deliver the EQUIVILENT of .05 units of U-100 insulin. In other
words, if the pump were using U-200 insulin, and you told it to give
you 1 unit of insulin, it would actually deliver .5 ul. That means
that the motor is capable of delivering insulin to that level of
resolution. So, in you use U-100 insulin, it is capable of
delivering .05 units of insulin. If you use U-50, then it is capable
of delivering .025 units of insulin.
So, it is simply a matter of a software change to support the .05 unit
resolution in the pump because the motor can handle it.
Now, concerning the existance of U-200. I read an interview on-line
that made it sound like there was GOING to be (or is in the works) an
attempt to get FDA approval for a U-200 insulin for pump use. It might
be possible that MM was trying to get ahead of the game by designing a
pump that could handle this (which might also explain the smaller
resoivoir size) new insulin. But, I also found some medical studies
that were done using U200 and U500 insulins, so perhaps U200 insulin IS
available for non-consumer use at this time.
>That seems bass-ackwards. If you infuse 1 ul (micro-liter) of U-200,
>then you've gotten 2 units of insulin. If you infuse 0.25 ul of
>U-200 insulin you've gotten 0.05 units. But there never was such a
>thing as U-200. They do have the U-50 settings in the Paradigm, and
>with that insulin (which should be relatively easy to formulate with
>the proper diluent) you could get a 0.05 basal rate. Does this mean
>that the 512 cartridge will only hold 88 units now of U-50 insulin?
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