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[IP] 24 hour urine test / blood draw

From: "Marty Chansler" <email @ redacted>
Subject: [IP] 24 hour urines tests
Just a quick question. My friends mom is a diabetic, and she had to do a 
hour urine test. They forgot to do the blood work the day that she took it 
but called her the following day, saying to come in to have it drawed. 
this cause a mistake in the test? She got a call from her doctors office
today, saying they wanted her to see a kidney specialist. My friend said 
than likely her mom wouldn't mention about the blood being drwan the next 
or anything. I know when I've done my 24 hour urine test, my nurse always 
to make sure to have blood drawn when droping it off, or it'd have to be
redone. Any thoughts on this??

I am an ASCP Medical Technologist and ran these tests for years when I was 
working Hospital Clinical Laboratory.  The test that was done was most 
likely a Creatinine Clearance.  The Creatinine clearance compares 
creatinine plasma levels with the creatinine that appears in the urine 
(usually over a 24 hour period).  The plasma levels remain fairly constant 
over time so it is unlikely that a 24 hour laps in the blood draw would 
significantly affect the results.  CLIA suggests that the blood is drawn 
during the time period of specimen collection.  Most clinical laboratory 
protocols give a 48 hour window for the blood draw.  It is unlikely that 
the next-day blood draw would have a significant affect on the overall 
Creatinine Clearance rate, and you were most likely within the laboratory 
protocol guidelines. Bottom line, it looks like the test exceeded the 
normal limits for creatinine clearance, and your friend's mom should see 
the specialist. Creatinine Clearance is a somewhat general test that has 
many variables too it (most which are more or equally significant than the 
time of the blood draw).The specialist will look more specifically at 
other factors to determine if the results were an indicative of kidney 

Mike Oberle
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