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[IP] Re: Bubbles in Insulin

So how long does it typically take a bottle of insulin
to get to room temp? And....how long do you know
before you have to change your reservoir...so you have
enough time to get the insulin to room temp?

Date: Mon, 15 Jul 2002 11:03:08 -0700 (PDT)
From: Christy Schneider <email @ redacted>
Subject: [IP] Re: Bubbles in Insulin (was ITCHING)

The reason comes from basic physics:  gases are more
soluble in liquids at lower temperatures.  Have you
ever noticed that a warm Diet Coke goes flat more
quickly than a cold one?  

If you fill a reservoir with cold insulin, the gases
that are in solution in the insulin may come out of
solution (in other words, form bubbles) as the
temperature of the insulin rises to room- or body-
temperature.  By filling the reservoir with
room-temperature insulin, you reduce one potential
source of bubbles.

If you never have problems with bubbles forming in
your reservoir, I wouldn't worry about this, but I
wanted to let you know the reasoning behind it.
- -Christy

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