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RE: [IP] Re: mixing V and H in the summer



So is the point of mixing Humalog and Regular to avoid potency problems?

> ----------
> From: 	email @ redacted[SMTP:email @ redacted]
> Reply To: 	email @ redacted
> Sent: 	Friday, July 24, 1998 10:40 AM
> To: 	email @ redacted
> Subject: 	[IP] Re: mixing V and H in the summer
> 
> Ted, for what it is worth I have been mixing H and V (5:1) ratio in a
> cartridge that lasts about 2 weeks for me.  EVen with the 90 degree
> temps I
> have seen no precipitates or clumping, nor have noticed any change in
> BG/insulin  ratio for the duration of any 2 week cycle.  My bottles
> are
> stored in the refigerator.  So I don't think anyone needs worry about
> mixing degradation at least for a 2 week period or heat degradation
> (of
> course I don't live in Texas).   Since the buffers for H and V are
> definitely different, there is always the possiblity that there will
> be
> some reaction after a longer period of time, but at the present time
> there
> is no evidence for this.  If I decide to go with the mixture all the
> time,
> I will have no qualms about just making up a bottle of the mixture and
> keeping in the fridge.
> -wm
> 
> > I switched to the Lilly insulin since my endo was asking his
> "friend" at
> > Lilly about possible problems with the H&R mix. Obviously they could
> > only comment on the issues involved in mixing their own insulins.
> > Officially they have never tested mixing Humalog with Regular, but
> we're
> > still waiting for their unofficial comments. I wanted to know if it
> was
> > acceptable to pre-mix H&R in its own bottle to make refilling the
> pump
> > quicker and simpler. There is a theoretical possibility that over a
> > period of time (ie longer than the week we have the two mixed in the
> > pump cartridge) the two insulins could interfere with each other.
> 
> Yes, you mentioned this before. I've started pre-mixing my Humalog and
> R
> in a separate bottle before loading my syringes. I only mix about 200
> H to
> 40 R at a time, which gets used up in 2 cycles, usually about 4 days.
> Seems to
> work well for me.
> 
> Ted Quick
> email @ redacted
> 
> _____________
> Wayne Mitzner
> Department of Environmental Health Sciences
> The Johns Hopkins School of Hygiene and Public Health
> 615 N. Wolfe St.
> Baltimore, MD 21205
> Tel. 410 614 5446
> Fax 410 955 0299
> 
> 
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