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[IP] CDC information on prevalence and incidence of Type 1 autoimmune



Melitta:
>>> This CDC document says "the incidence of IDDM is about 30,000 new cases
each year.....the number of children who develop IDDM each year is about
13,000."  That means that 17,000 (57%, or the majority) of new cases of IDDM
are adults. <<<
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Based on your quote from the cited document, your conclusion seems
straightforward and accurate.  However, the number of 13,000 children is
used by the document in a different context and cannot be related to adult
onset of IDDM.  The 13,000 compares the incidence of IDDM with other
childhood diseases and defines the group as <=16 years of age.  The document
uses other criteria to establish *childhood* within the context of
comparison to adult onset IDDM.  That significantly alters your calculated
17,000 adults or 57%.


This is clearly spelled out in the document you cite as follows:
"The incidence of IDDM among children age <=19 years in Allegheny County, PA
is 18.2 per 100,000/year.  Applying this rate to the U.S. population, an
estimated 13,171 new cases arise each year in persons age <=19 years.

Applying the overall rate of 9.2 per 100,000 per year to the adult U.S.
population, an estimated 16,542 cases of IDDM arise each year in persons age
>=20 years in the United States.  Therefore, about 29,713 Americans develop
IDDM each year."

It clearly states:
The incidence in children is 18.2 per 100,000/year and ...
The incidence is 9.2 per 100,000 per year to the adult U.S. population.

That make the incidence in children approximately twice the incidence in
adults.  The larger adult population, however, gives a higher prevalence and
therefore a larger number of adults with IDDM, which you correctly point
out.

John Kinsley
Type 1 - 1956
MiniMed 507 - 1998
.
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