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[IP] Breastfeeding abstract

It seems there's always a study to refute the benefits found in another study 

Diabetes Care 2002 Jan;25(1):16-22  

Long-Term Impact of Neonatal Breast-Feeding on Body Weight and Glucose 
Tolerance in Children of Diabetic Mothers.

Plagemann A, Harder T, Franke K, Kohlhoff R.

Institute of Experimental Endocrinology, Humboldt University Medical School 
(Charite), Berlin. Clinic of Obstetrics and Gynecology, Berlin-Kaulsdorf, 
Berlin, Germany.

OBJECTIVE-Offspring born to women with pregnancies complicated by diabetes 
are at increased childhood risk of developing obesity and impaired glucose 
tolerance (IGT). In population-based studies, breast-feeding has been shown 
to be protective against obesity and diabetes later in life. To date, the 
role of breast-feeding on offspring of diabetic mothers (ODM) has not been 
investigated in this context. RESEARCH DESIGN AND METHODS-A total of 112 ODM 
(type 1 diabetes, n = 83; gestational diabetes, n = 29) were evaluated 
prospectively for impact of ingestion of either diabetic breast milk (DBM) or 
nondiabetic banked donor breast milk (BBM) during the early neonatal period 
(day 1-7 of life) on relative body weight and glucose tolerance at a mean age 
of 2 years. RESULTS-There was a positive correlation between the volume of 
DBM ingested and risk of overweight at 2 years of age (odds ratio [OR] 2.47, 
95% CI 1.25-4.87). In contrast, the volume of BBM ingested was inversely 
correlated to body weight at follow-up (P = 0.001). Risk of childhood IGT 
decreased by increasing amounts of BBM ingested neonatally (OR 0.19, 95% CI 
0.05-0.70). Stepwise regression analysis showed volume of DBM to be the only 
significant predictor of relative body weight at 2 years of age (P = 0.001). 
CONCLUSIONS-Early neonatal ingestion of breast milk from diabetic mothers may 
increase risk of becoming overweight and, consequently, developing IGT during 
childhood. Additional studies are needed to assess long-term consequences 
that might result from the type of neonatal nutrition in ODM.

PMID: 11772895 [PubMed - as supplied by publisher]  
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