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[IP] Antibiotics-Coated Catheters Urged

 I have a friend whose 12 year old was only getting 24 hours with the Tender
and Humalog.  Then white stuff would build up in the cannula and he'd have to
change it.  Tired of changing it so frequently, they tried various cocktails
of H:R, to no avail.  Now he's using R in the pump for basal only and H in the
pen.  He's hit that time where he needs much greater quantities of insulin
than ever before.  That's being satisfied with this method, but it seems so
unfair to have to use the pump for only the basal insulin.  I wonder if the
polymer of the tender needs to be changed in order to use the H.  (My son is
still getting 3.5 full days out of the Tender and H without a problem.)  Her
son doesn't like the sof-sets because they go straight in and are too deep for
his slender ab area.


ps. Found this on AP - wonder if it would be helpful for people prone to site
or if introducing yet more antibiotics would further complicate ....

Antibiotics-Coated Catheters Urged

By The Associated Press

Coating catheters with antibiotics can greatly reduce a major source of
infection among hospital patients, researchers reported today in the New
England Journal of Medicine.

Catheters are extremely thin, flexible tubes used to introduce drugs,
anesthesia or food into a patient via a blood vessel. They may be used
for a few hours or remain in place for weeks during treatment for heart
disease, cancer and other major diseases.

>From 150,000 to 200,000 Americans are infected each year when germs are
accidentally introduced into the bloodstream by a catheter. An estimated
25 percent die.

Some researchers are experimenting with bonding antibacterial agents to
catheters to try to cut the rate of infection.

The study compared catheters saturated inside and out with the
antibiotics minocycline and rifampin to catheters coated on the outside
only with two antibacterial agents  chlorhexidine and silver

Only one catheter-related infection occurred among the 350 patients who
got catheters impregnated with minocycline and rifampin, compared with
13 among the 370 patients who got catheters coated with chlorhexidine
and silver sulfadiazine.

Both types of catheters led to lower infection rates than other studies
have found in catheters without antibacterial agents.

The study was led by Dr. Rabih Darouiche of Baylor College of Medicine
in Houston and Dr. Issam Raad of the University of Texas M.D. Anderson
Cancer Center. The two men invented the technology for impregnating
catheters with minocycline and rifampin and earn royalties as a result.

Insulin-Pumpers website http://www.insulin-pumpers.org/