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[IP] Re: Diluting

Hi Paula---I think I've read all the comments so far about diluting.  
There are a "few adult IPers" out here, me and a tiny group that I know 
(besides the children in the group), who did the dilution routine (with 
Humalog) for the first years on our MiniMed pumps that delivered only 
.1u at a time, nothing smaller. It was just too big a dose especially 
when delivered only once or twice an hour (eg., with a .2 or .1 basal), 
but also sometimes too small to keep the pump running 
smoothly---possible clogging, etc. We diluted 1:1 or even 1:4 to get 
the right concentration possibilities, essential for basals. We 
obtained "free" diluent from Eli Lilly, delivered directly to the 
pharmacist of one's choice who called in the order for it.

Everyone who answered you is absolutely right---NO to water as a 
diluent--that is crazy!!!!!!!  However, within the past year, I "think" 
I read that diluent production was being discontinued by Lilly and I 
can perhaps guess why if that's true.  Although the diluent was a great 
solution for producing smaller concentrations of insulin, the newer 
pumps with smaller and more frequent basal delivery changed the picture 
completely.  I was thrilled to get my Animas 1000 with the .05 basal 
possibility and even better, the upgrade to the Animas 1200 with the 
.025 basal variations.  Unfortunately, you may not be in a position to 
get a pump right this minute with the appropriate delivery 
possibilities for you.  It does make an enormous difference when you 
use small amounts of insulin.  You absolutely need the insulin you get 
but the differences in those small amounts can really affect how you 
feel. Dilution is relatively easy but if you need to do it I would call 
Lilly and check about the availability of diluent these days.


Date: Wed, 2 Feb 2005 09:49:14 -0500
From: "Paula Bosarge" <email @ redacted>
Subject: [IP] diluted insulin

My minimed rep/advisor wants me to dilute my insulin with water - tap
water - so that I'd be using a solution of 50% humalog & 50% water.  
been having trouble with my sites lasting long enough, and she's 
it's because my basal rates aren't high enough.  I stay @ .2 all day 
for a few hours during the morning.  For the past 2 weeks, however, all 
my sites - I use silhouettes - have lasted 3 or 3 1/2 days!)  Does 
else dilute their insulin?  This really scares me!!  What if I don't 
get the
water measured perfectly?  Wouldn't it just be easier to use a U-50 
My advisor said U-50 was an option, but she preferred to dilute hers.  
used to dilute when she was smaller & had lower basals.)
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