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Re: [IP] Re: Coffee & BG
In a message dated 2/24/03 11:41:31 AM US Eastern Standard Time,
email @ redacted writes:
<< his thread has popped up many times on IP over the years. There is
no reliable study that has shown coffee to have any effect on BG. >>
Sure there has:
Caffeine Shown to Lower Insulin Sensitivity
Exercise Could Help Counter the Effects of Caffeine-Induced Insulin Resistance
Caffeine, a component of many popular dietary sources such as coffee,
tea, colas and chocolate, decreases insulin sensitivity by 15 percent in
people without diabetes, say researchers in the Netherlands. The doctors, who
conducted a small test group study, published their findings in the February
2002 issue of Diabetes Care.
Researchers from the University Medical Center in Nijmegen injected doses
of caffeine equal to moderate consumption into 12 healthy individuals and
doses of a placebo (inactive) substance into 10 individuals after all the
subjects had abstained from caffeine for 72 hours.
The decrease in insulin sensitivity documented during the caffeine trial
neared the magnitude of the increase in insulin sensitivity that can be
achieved by taking oral insulin-sensitizing agents, researchers say. In
addition, the caffeine group had higher blood levels of free fatty acids and
increased levels of the hormone adrenaline, which causes the liver to release
glucose and limits the release of insulin.
The increase of adrenaline may be causing the decrease in insulin
sensitivity, the researchers speculate. They point out that further studies
need to determine whether the decreased insulin sensitivity continues over
time with chronic use of caffeine. Because tolerance may develop with
long-term ingestion of caffeine, they add, it's premature to advise caffeine
restriction to manage insulin resistance.
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