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Re: [IP] Humolog not working....

the only times I have problems getting sugars down with humalog, is withing
hours of a low in the middle of a rebound.

----- Original Message -----
From: "Deborah" <email @ redacted>
To: <email @ redacted>
Sent: Wednesday, February 12, 2003 2:13 PM
Subject: Re: [IP] Humolog not working....

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> ChriS,
> I've replied to both of your e-mail here.
> My daughter Eve who is 15.5  has diabetes and Humalog has always worked
> inconsistently for her. The same things have happened to her as you.
> Sometimes a high bolus will bring her down fine and other times she will
> very low in four hours (like this morning). We too thought that some how
> insulin was going bad in a short amount of time or was handle wrong in
> shipping or at the pharmacy.
> When she was in the hospital in Dec. in DKA (gave her 45 units at a time
> her number would not budge)her endo had her tested for antibodies against
> pork and beef insulin and insulin analogs such as Humalog and Novolog. It
> turns out that she is resistant to pork and beef insulin and insulin
> analogs. She is 19% resistant to beef insulin and insulin analogs and 13%
> resistant to pork insulin. Normal resistant is less than 3%.
> Her endo said they put kids who are resistant to insulin analogs on pumps.
> Eve has been on a pump for close to 4 years now. I have been searching on
> the internet for information about insulin analog resistant or antibodies
> against insulin analogs since I was told this. I haven't found any
> information. My next step is to call someone that handled the DPT studies
> the U of Minn. thinking that someone there would know something.
> Perhaps, some doctor here on this e-mail site might know more about this.
> Deborah mom to Eve 15.5, and her pump
> Dxed 5/3/96 pumping 5/21/99
> > Has anyone else felt that Humolog / Novorapid (and Toronto) seem to work
> > inconsistently?
> >
> > Thoughts?
> >
> > Thanks,
> >
> > ChriS
> >I have noticed that some times, I have to take more
> >insulin than usual to bring my sugars down, other times, the dosage
> >creates a nasty low.
> >ChriS
> > ----------------------------------------------------------
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> ----------------------------------------------------------
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