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Re: [IP] Sliding Scale Insulin Dose



Your diabetes specialist has an interesting theory here, but it has holes,
one of the most major ones being that a _non_-diabetic's beta cells secrete
the appropriate amount of insulin required to cover the rise in BG levels
caused by the food that was just eaten.  This might be 6 units, 10 units, 14
units, or any other amount.  It isn't a 'body cycle' type of thing; it's a
direct response to the food that you happen to choose to eat, when you
choose to eat it.  This is something that we try to mimic with the bolus
functions of our insulin pumps.

The basal insulin that a non-diabetic's beta cells produce, however, _is_ a
rhythmic daily process, and this is something that we _also_ try to mimic
with the basal rate programming in our pumps.

I don't think your diabetes specialist's argument holds enough water to
warrant you having second thoughts...

DanO
--------
At 01:01 2/24/98 +0100, John wrote:
>I've posted on this already, but I've had some 2nd thoughts. Another diabetes
>specialist I see in London explained it to me like this: the body's hormone
>system is very complex, and not well understood, but it works in a 24 hour
>cycle. The body can withstand interuptions to it's cycle (being woken in the
>night, missing a meal, that sort of thing) but we all function best when we
>are in a routine. If your body is used to receiving 10 units of insulin at
>midday, then it grows to expect it. So as midday approaches, all sorts of tiny
>and subtle changes take place in the body, in preparation for it's insulin
>bolus and food. If you suddenly give it 6 units or 14 units instead, you upset
>it's balance slightly. So in general it's best for the body to set up a
>regular cycle of insulin injection, and stick to it.
>
>That was his view, and he seemed to know his stuff. Perhaps there's something
>in it, but personally I believe it's irrelevent compared with the damage to
>your body's cycle that high and low bg's do. I've been on my pump 2 months
>now, and have never felt so happy and well before, but then I now have both
>stable bg's AND a stable basal dose. It's just my boluses that vary with what
>I eat, and that varies with everyone, diabetic or not.
>
>John Neale
>Type 1, 21 years, MiniMed507+Humalog for 2 months and still in "euphoria"
>stage.

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