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Re: [IP] Humalog potency loss?


I just joined the list and haven't read through the archives, so please
forgive me if I'm rehashing an old beat-to-death topic...

I find it difficult to believe (in my case) that 'infusion site corruption'
is what causes the problem, since I don't change the infusion site at all.
I merely change the insulin in the reservoir and tubing.  Same infusion
site, infusion set, tubing, and reservoir.  No repriming of the set either,
just the tubing itself.

At 15:04 2/5/98 +0000, you wrote:
>> I've been pumping Humalog exclusively for a little less than a year now, and
>> noticed early on the potency loss (of the Humalog ;-) that you mention.
>> I'm not sure why this occurs, but it may be temperature related.  The
>> Humalog in the tubing is kept (in my case) at pretty darn near 98F or so, or
>> maybe even warmer during the summer.  The package insert indicates that it
>> should never be stored above 86F.
>> Anyhow, I found that if I reload the pump reservoir (and reprime the tubing)
>> every 2 days, I notice very little loss of potency.
>> Anyone else have any experience with this?
>Yes, there has been extensive discussion on the list (see the 
>archives) but the bottom line is that it's probably a result of 
>infusion site corruption.  Mixing a little regular with the H seems 
>to help.  My daughter and several others mix H/V in a 5/1 ratio.
>email @ redacted