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Re: [IP] Bursting Bubbles, from minimed web site

Good ideas Christine.  If you store the insulin with a lot of vacuum in the
refrigerator, that will also help to degas the insulin.  Just draw out a
lot of air from the bottle when you store it.  However, when you next go to
fill,  make sure to first let the air pressure come back to normal (just
poke a needle in the top of an upright bottle).   Sucking against a
negative pressure will generate bubbles by itself.  And the short amount of
time needed for filling won't put any more air into solution.  Then when
done, draw out the air out of the bottle for storage again.
	Also if you do get small bubbles in the syringe, I find that
tapping with a hard object (metal pen, screwdriver handle,,etc) is much
more effective than using my fingernail.  I think the hard objects set up
higher frequency pressure waves that moe easily release the tiny bubbles.

<<<<<<<<<<From: Christene Ullom <email @ redacted>
Did you know that when refrigerated insulin warms to room temperature, air
bubbles come out of the solution? This can also happen when room temperature
insulin is warmed to body temperature. If you take these simple measures,
you can minimize the amount of air that can accumulate in your infusion set
and reservoir.
	First, it is always best to let insulin warm to room temperature
before you
fill your reservoir, but if you must use insulin straight out of the fridge,
or if the bottle feels cold, try this:
	Create a vacuum in the air space at the top of the insulin vial.
You can do
this with the syringe/reservoir you are about to fill. Push the plunger all
the way in, insert the filling needle into the air space in he insulin vial,
then withdraw a full 3 cc's of air. Holding the plunger back, remove the
needle from the vial. Now shake the vial vigorously for about five seconds
and let it sit for 5 minutes. The vacuum will remove most of the air from
the insulin. You can then proceed with filling your reservoir as usual.
	If you notice bubbles in your reservoir, after you've filled it,
pull back
the plunger and draw some additional air into the reservoir. Hold the
reservoir by the base of the plunger, pointing up, and gently tap the
reservoir until all of the little air bubbles have combined into one at the
top of the reservoir, then slowly and gently push the plunger until all of
the air is out.
Finally, don't be overly concerned about tiny bubbles. One inch of air in
the tubing equals one half of a unit of U-100 insulin, and it takes a lot of
tiny bubbles to equal one inch. >>>>>>>>>>>>>

Wayne Mitzner
Department of Environmental Health Sciences
The Johns Hopkins University
615 N. Wolfe St.,  Baltimore, MD 21205
Tel. 410 614 5446,   Fax 410 955 0299

Insulin-Pumpers website http://www.insulin-pumpers.org/