[IP] Found something on Pizza boluses!
FWIW, I found this item on the MSN pumpers site. Naturally, YMMV, but it
seems to make some interesting conclusions:
Pizza Testing and Insulin Control
Message 4 in Discussion
Pizza testing and insulin control. This is reported in the Diabetes
interview. http://www.insulin-pumpers.org/cgi/chat/chatset.plx Abstract Title
Insulin Pump Dosing and Postprandial Glycemia Following a Consistent Pizza Meal
Abstract Information Abstract Number: 2314-PO Authors: SUSAN M. JONES, JILL
L. QUARRY-HORN, DAVID T. MAUGER, PHILLIP G. FEDAKO, ROBERT A. GABBAY
Institution: Hershey, PA Results: Objective -- To identify an optimal insulin
bolus by comparing postprandial sensor glucose values following three methods
of insulin pump meal bolusing for a consistent pizza meal. Research Design and
Methods -- A group of 26 self-selected patients with type 1 diabetes using
continuous subcutaneous insulin infusion with insulin lispro participated in a
study to compare postprandial sensor glucose values following three (3) meal
bolus regimens for a consistent evening meal of plain, cheese pizza. Each
participant utilized the following insulin regimens on successive evenings and
glucose values were tracked by the Continuous Glucose Monitoring System (CGMS):
1) insulin dose calculated with standard evening meal insulin/carbohydrate
ratio; given as normal (immediate) bolus. Day 2) same total insulin dose
programmed as dual wave with 50% given as normal bolus and 50% over 4 hours.
same total insulin dose programmed as dual wave with 50% given as normal bolus
and 50% over 8 hours. Results [ndash]Bolus delivery over 8 hours (day 3)
provided significantly better postprandial glycemia, than either day 1 or day 2
Day 1 vs. day 3 shows a statistically significant 24% reduction in day 3 mean
glucose (8.4mmol/l vs. 7 mmol/l; P < 0.02); percentage of time in range was
significantly increased in day 3 (32% day 1 vs. 49% day 3; P<0.01) with no
difference in time below range. Percentage of time above the curve (53% vs.
P<0.015) and area above the curve (36 vs. 21; P< 0.01) were decreased on day 3.
Comparing day 2 vs. day 3: statistically significant reduction in mean glucose
on day 3 (8mmol/l vs. 5.7 mmol/l respectively; P< 0.01); percentage of time
above the curve (43% vs. 20% respectively; P< 0.037) and area above the curve
(34 vs. 9 respectively; P< 0.01) were significantly decreased on day 3.
Conclusions -- For a consistent pizza meal, insulin administered as a dual wave
with 50% of the total delivered over 8 hours provided significantly less
postprandial hyperglycemic exposure with no increase risk of hypoglycemia.
Category: Insulin Action
Thanks, and God Bless You,
Alexander N. Gerli
949 Hopmeadow St., Apt. 2
Simsbury, CT 06070
for HELP or to subscribe/unsubscribe, contact: