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[IP] Our hope is in Lizard Spit? 8-)

>From Yahoo health headlines, Reuters News
Lizard Spit Drug Controls Diabetes, Cuts Weight
Mon Aug 25,12:54 PM ET
PARIS (Reuters) - Exenatide, an experimental diabetes drug derived from 
 lizard saliva, not only controls patients' blood sugar levels but also cuts
weight, its developers said on Monday. 
Amylin Pharmaceuticals Inc and Eli Lilly and Co released new study findings 
 on the efficacy of exenatide at the 18th Congress of the International Diabetes
Federation in Paris. The drug, derived from the saliva of a lizard known as 
the Gila monster, is the first in a new class of therapies for type 2, or 
 adult-onset, diabetes and is on track to be submitted for approval by
regulators in
2004. Analysts forecast annual sales could top $500 million after three 
 years. The Gila monster lizard lives in the Arizona desert, only eating about
times a year. Its salivary secretions help prevent a sudden surge in blood 
sugar levels in response to these infrequent but large meals. The latest 
 exenatide test involved 155 patients who had failed to reach target glucose
levels on
established diabetes drugs metformin and sulfonylurea, or a combination of the 
two. When researchers added injections of exenatide, 44 percent of patients 
who completed 24 weeks of treatment achieved glucose level averages within the 
target range, the companies said. Patients also lost on average 7.5 pounds. 
Amylin CEO, Dan Bradbury, told Reuters that being able to control the blood 
 sugar levels of so many patients who had previously failed therapy was a
exciting result." The most frequently reported side effect in the study was 
mild to moderate nausea, which decreased with continued treatment. 
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