apply the insertion set, use whatever you feel necessary to relieve 'discomfort' during the insertion of the device. This could be as simple as put ice on the chosen site for a few moments, or as involved as using EMLA cream or anesthetic disks(a prescription item).
Apply an anti-bacterial (I use Smith and Nephew I.V. Prep).
An application of an antibacterial skin preparation will help by making the skin sticky and also serve as a barrier between the skin and the adhesive. Smith and Nephew Skin Prep or IV Prep are most often mentioned but there is also ShieldSkin by the Mentor Company and Skin Tac by Mason Labs (and probably more). There is also
3M
No Sting Barrier Film. The 3M product description includes that No-Sting is a "professional" product. The uses listed for the product are protective but this has been used by some pumpers with some success. Plain antiseptics or antibacterials, such as Hibiclens or Betadine will help prevent infection but are not intended to aid in adhesion.
With the safety loop taking the force of a tug or pull, the adhesive on the cannula will have only to stay on you, rather than also having to resist those tugs.